Tesamorelin Research Peptide for Sale

Tesamorelin

Tesamorelin research peptide for sale at 99%+ purity, verified by HPLC and mass spectrometry, with a batch-specific Certificate of Analysis available before you order. Supplied by NuScience Peptides from the USA for laboratory and analytical research use only.

What Is Tesamorelin?

Tesamorelin is a stabilized synthetic analog of growth hormone-releasing hormone (GHRH), a 44-amino-acid peptide with an added trans-3-hexenoyl group that improves stability over native GHRH. In preclinical research it is used to study GHRH-receptor activity and the somatotroph signaling that governs growth hormone secretion, which is why it appears in metabolic and endocrine research models.

Tesamorelin Purity and COA Verification

Every batch is independently third-party tested in the USA and verified by HPLC and mass spectrometry to confirm identity and 99%+ purity, with a batch-specific Certificate of Analysis published for each lot. To compare specifications across the catalog, browse all research peptides.

Buy Tesamorelin Research Peptide Online

NuScience Peptides supplies tesamorelin in research-grade vials. Orders placed before 12 PM EST ship the same day from the USA, with free shipping over $200. For the full range of research peptides for sale, check the Certificate of Analysis for any batch before you order.

This product is not intended for weight loss, human consumption, or veterinary use. It is sold for research purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved.

Tesamorelin MUST be reconstituted with 3ml STERILE water (Not BAC),

and

the peptide as well as water must be kept at room temperature prior to reconstitution.

Tesamorelin: GH Secretion and Metabolic Effects in Rat Models

Administering tesamorelin to rats has been shown to enhance endogenous GH pulsatility, leading to increased insulin-like growth factor I (IGF-I) levels without adversely affecting insulin sensitivity. This suggests its utility in studying metabolic regulation and endocrine function in animal models.

Tesamorelin Peptide: Muscle Composition and Adipose Tissue Research

Beyond metabolic effects, tesamorelin has demonstrated the ability to reduce muscle fat and increase muscle area in clinical studies, indicating its potential for investigating muscle composition and function in rats. Such findings are particularly relevant for exploring interventions in muscle-wasting conditions.

Additionally, tesamorelin has been observed to improve fat quality independent of changes in fat quantity, highlighting its role in adipose tissue research. This property makes it a valuable tool for studying the qualitative aspects of fat tissue and their implications on overall metabolic health.

Furthermore, research indicates that tesamorelin may enhance cognitive function, including improvements in executive function and verbal memory. These cognitive benefits open avenues for exploring its effects on brain function and neuroendocrine interactions in rodent models.

Tesamorelin: Research Summary and Preclinical Outlook

In summary, tesamorelin’s multifaceted effects on GH secretion, muscle composition, adipose tissue quality, and cognitive function make it a promising compound for comprehensive rat studies aimed at understanding metabolic and neuroendocrine dynamics.

Buy tesamorelin from NuScience Peptides to advance your growth hormone research. Explore related GHRH compounds including the Tesamorelin/Ipamorelin blend for synergistic GH-axis studies and Sermorelin for comparative GHRH analogue research. Use our Peptide Calculator to determine reconstitution volumes.

References:

1. Stanley, T. L., Chen, C. Y., Branch, K. L., Makimura, H., & Grinspoon, S. K. (2011). Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men. The Journal of Clinical Endocrinology & Metabolism, 96(1), 150–158. https://pubmed.ncbi.nlm.nih.gov/20943777/
2. Adrian, S., Scherzinger, A., Sanyal, A., Lake, J. E., Falutz, J., Dubé, M. P., … & Erlandson, K. M. (2019). The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV. The Journal of Frailty & Aging, 8(3), 154–159. https://pmc.ncbi.nlm.nih.gov/articles/PMC6766405/
3. Lake, J. E., Moser, C., Johnston, L., Magyar, C., Nelson, S. D., Erlandson, K. M., … & Stanley, T. L. (2021). Tesamorelin Improves Fat Quality Independent of Changes in Fat Quantity. The Journal of Clinical Endocrinology & Metabolism, 106(7), e2710–e2718. https://pmc.ncbi.nlm.nih.gov/articles/PMC8243807/
4. Baker, L. D., Barsness, S. M., Borson, S., Merriam, G. R., Friedman, S. D., Craft, S., & Peskind, E. R. (2011). O3‐07‐08: Tesamorelin, a growth hormone‐releasing hormone analogue, improves cognitive function in MCI and healthy aging: Results of a randomized controlled trial. Alzheimer’s & Dementia, 7(4), S608. https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1016/j.jalz.2011.05.1439
5. Clemmons, D. R., Miller, S., & Mamputu, J. C. (2017). Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial. PLoS ONE, 12(6), e0179538. https://pmc.ncbi.nlm.nih.gov/articles/PMC5472315/

NuScience Peptides has tesamorelin peptide for sale in both 10mg and 20mg research-grade formats – strictly for laboratory use, not for human consumption.

ALL LITERATURE, INFORMATION, AND DATA, PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

Properties

Molecular Formula	C221H366N72O67S
Molecular Weight	5136
Monoisotopic Mass	5132.7166406
Polar Area	2360
Complexity	12800
XLogP	-23.3
Heavy Atom Count	361
Hydrogen Bond Donor Count	83
Hydrogen Bond Acceptor Count	76
Rotatable Bond Count	187
Physical Appearance	Fine White Lyophilized Powder
Stability	Lyophilized protein is to be stored at -20°C. It is recommended to aliquot the reconstituted (dissolved) protein into several discrete vials in order to avoid repeated freezing and thawing. Reconstituted protein can be stored at 4°C
PubChem LCSS	Tesamorelin Laboratory Chemical Safety Summary

Identifiers

CID	16137828
CAS	218949-48-5
InChI	InChI=1S/C221H366N72O67S/c1-25-28-30-53-163(308)260-145(92-120-54-58-122(299)59-55-120)198(343)255-116(21)179(324)276-150(96-169(316)317)199(344)256-117(22)180(325)291-172(111(16)26-2)214(359)284-147(91-119-43-31-29-32-44-119)206(351)293-174(118(23)298)215(360)285-149(95-162(230)307)205(350)289-155(104-297)210(355)280-146(93-121-56-60-123(300)61-57-121)203(348)267-130(51-41-83-248-220(240)241)186(331)266-126(46-34-36-78-223)197(342)290-171(110(14)15)212(357)283-141(87-106(6)7)183(328)252-100-166(311)258-133(63-70-157(225)302)190(335)278-144(90-109(12)13)202(347)288-152(101-294)208(353)257-115(20)178(323)262-128(49-39-81-246-218(236)237)185(330)265-125(45-33-35-77-222)189(334)277-143(89-108(10)11)201(346)279-142(88-107(8)9)200(345)272-137(66-73-160(228)305)195(340)282-151(97-170(318)319)207(352)292-173(112(17)27-3)213(358)274-139(76-85-361-24)196(341)287-153(102-295)209(354)268-131(52-42-84-249-221(242)243)187(332)270-135(64-71-158(226)303)192(337)269-132(62-69-156(224)301)182(327)251-99-165(310)259-134(67-74-167(312)313)191(336)286-154(103-296)211(356)281-148(94-161(229)306)204(349)273-136(65-72-159(227)304)193(338)271-138(68-75-168(314)315)194(339)264-124(47-37-79-244-216(232)233)181(326)250-98-164(309)253-113(18)176(321)261-127(48-38-80-245-217(234)235)184(329)254-114(19)177(322)263-129(50-40-82-247-219(238)239)188(333)275-140(175(231)320)86-105(4)5/h28-32, 43-44, 54-61, 105-118, 124-155, 171-174, 294-300H, 25-27, 33-42, 45-53, 62-104, 222-223H2, 1-24H3, (H2, 224, 301)(H2, 225, 302)(H2, 226, 303)(H2, 227, 304)(H2, 228, 305)(H2, 229, 306)(H2, 230, 307)(H2, 231, 320)(H, 250, 326)(H, 251, 327)(H, 252, 328)(H, 253, 309)(H, 254, 329)(H, 255, 343)(H, 256, 344)(H, 257, 353)(H, 258, 311)(H, 259, 310)(H, 260, 308)(H, 261, 321)(H, 262, 323)(H, 263, 322)(H, 264, 339)(H, 265, 330)(H, 266, 331)(H, 267, 348)(H, 268, 354)(H, 269, 337)(H, 270, 332)(H, 271, 338)(H, 272, 345)(H, 273, 349)(H, 274, 358)(H, 275, 333)(H, 276, 324)(H, 277, 334)(H, 278, 335)(H, 279, 346)(H, 280, 355)(H, 281, 356)(H, 282, 340)(H, 283, 357)(H, 284, 359)(H, 285, 360)(H, 286, 336)(H, 287, 341)(H, 288, 347)(H, 289, 350)(H, 290, 342)(H, 291, 325)(H, 292, 352)(H, 293, 351)(H, 312, 313)(H, 314, 315)(H, 316, 317)(H, 318, 319)(H4, 232, 233, 244)(H4, 234, 235, 245)(H4, 236, 237, 246)(H4, 238, 239, 247)(H4, 240, 241, 248)(H4, 242, 243, 249)/b30-28+/t111-, 112-, 113-, 114-, 115-, 116-, 117-, 118+, 124-, 125-, 126-, 127-, 128-, 129-, 130-, 131-, 132-, 133-, 134-, 135-, 136-, 137-, 138-, 139-, 140-, 141-, 142-, 143-, 144-, 145-, 146-, 147-, 148-, 149-, 150-, 151-, 152-, 153-, 154-, 155-, 171-, 172-, 173-, 174-/m0/s1
InChIKey	QBEPNUQJQWDYKU-BMGKTWPMSA-N
Isomeric SMILES	CC/C=C/CC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N
Canonical SMILES	CCC=CCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)N
IUPAC Name	(4S)-4-[[2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S, 3S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S, 3R)-2-[[(2S)-2-[[(2S, 3S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-2-[[(2S)-2-[[(E)-hex-3-enoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentanoyl]amino]-3-carboxypropanoyl]amino]-3-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-5-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1, 5-dioxopentan-2-yl]amino]-1, 4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid